By C.G. Bernhard and J.P. Schadé (Eds.)
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Additional resources for Developmental Neurology
Epithelial fibers extend from the germinal zone towards the surface. Their general ditection has been outlined in Fig. 11. 5-g fetus. The inner part is made up of densely packed cells which form columns outside the internal limiting membrane. Mitoses are rare in contrast to those seen in younger animals. The cells in the outer part are separated to some extent by a fine network of fibrils. The nuclei are usually smaller, darker and more pleomorphic than those in the inner sublayer, but some scattered, larger and lighter nuclei are also seen.
1) The axon collaterals of pyramidal cells in the middle third of the layer have developed considerably. They frequently have a more or less horizontal course and are, therefore, largely distributed within the same stratum as the corresponding cell bodies (Fig. 18B; 4, 5). (2) Numerous stellate cells have appeared in the pyramidal layer (11-14). e. serve as interneurons. Similar cells are seen in the outer part of the intermediate zone (9-lo), as they had been from the 12-g stage onward. Well developed Martinotti cells are also present in the pyramidal layer (Fig.
39-gram fetus, estimated age 57 days. Coronal section at level of genu of corpus callosum (Co c). Similar features as in Fig. 10. General direction of radiating fibers indicated by lines. Cresyl violet, x 15. -E. ASTROM lie in clusters or rows between the circulating fibers. They have peripheral processes, and some also emit thin extensions in a central direction. Furthermore, there are some larger nuclei with light chromatin, and one or two nucleoli. The outer part of the intermediate zone lacks the circulating fibers but there are numerous cells, many of which are more highly differentiated than those in the inner part.